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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Pou5f1-GFP)1Scho
transgene insertion 1, Hans R Scholer
MGI:3693125
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Baxtm1Sjk/Baxtm1Sjk
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/? 		involves: 129X1/SvJ * C3H * CD-1 * FVB MGI:3693197
cx2
 		Baxtm1Sjk/Bax+
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/? 		involves: 129X1/SvJ * C3H * CD-1 * FVB MGI:3693198


Genotype
MGI:3693197
cx1
Allelic
Composition		 Baxtm1Sjk/Baxtm1Sjk
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/?
Genetic
Background		 involves: 129X1/SvJ * C3H * CD-1 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
KitlSl mutation (3 available); any Kitl mutation (92 available)
Tg(Pou5f1-GFP)1Scho mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal primordial germ cell migration ( J:115283 )
• defective germ cell migration out of the hindgut
abnormal primordial germ cell proliferation ( J:115283 )
• decreased germ cell proliferation
• normal apoptosis of primordial germ cells

cellular
abnormal primordial germ cell migration ( J:115283 )
• defective germ cell migration out of the hindgut
abnormal primordial germ cell proliferation ( J:115283 )
• normal apoptosis of primordial germ cells
• decreased germ cell proliferation




Genotype
MGI:3693198
cx2
Allelic
Composition		 Baxtm1Sjk/Bax+
KitlSl/KitlSl
Tg(Pou5f1-GFP)1Scho/?
Genetic
Background		 involves: 129X1/SvJ * C3H * CD-1 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
KitlSl mutation (3 available); any Kitl mutation (92 available)
Tg(Pou5f1-GFP)1Scho mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal primordial germ cell proliferation ( J:115283 )
• increased apoptosis of primordial germ cells
• decreased germ cell proliferation

cellular
abnormal primordial germ cell proliferation ( J:115283 )
• increased apoptosis of primordial germ cells
• decreased germ cell proliferation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory