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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Camta2tm1Eno
targeted mutation 1, Eric N Olson
MGI:3692751
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Camta2tm1Eno/Camta2tm1Eno involves: 129S/SvEv * C57BL/6 MGI:3696714


Genotype
MGI:3696714
hm1
Allelic
Composition		 Camta2tm1Eno/Camta2tm1Eno
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Camta2tm1Eno mutation (0 available); any Camta2 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased response of heart to induced stress ( J:115868 )
• ability to mount a hypertrophic response to stress is compromised as mutants in response to thoracic aortic banding show only a 22% increase in cardiac mass compared to a 60% increase in wild-type
• cardiac hypertrophy is suppressed in mutants following chronic infusion with angiotensin II and the adrenergic agonist isoproterenol

homeostasis/metabolism
decreased response of heart to induced stress ( J:115868 )
• ability to mount a hypertrophic response to stress is compromised as mutants in response to thoracic aortic banding show only a 22% increase in cardiac mass compared to a 60% increase in wild-type
• cardiac hypertrophy is suppressed in mutants following chronic infusion with angiotensin II and the adrenergic agonist isoproterenol




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory