About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Tnnt2*R92Q)1Lnwd
transgene insertion 1, Leslie A Leinwand
MGI:3692448
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Tnnt2*R92Q)1Lnwd/0 involves: C57BL/6 MGI:5755251


Genotype
MGI:5755251
tg1
Allelic
Composition		 Tg(Myh6-Tnnt2*R92Q)1Lnwd/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart atrium morphology ( J:56911 )
• progressive atrial hypertrophy
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers
abnormal heart ventricle morphology ( J:56911 )
• ventricular mass decreases by about 18%

muscle
abnormal sarcomere morphology ( J:56911 )
• sarcomere lengths are shorter in left ventricular myocytes

growth/size/body
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory