All Phenotypes Tg(Myh6-Tnnt2*R92Q)1Lnwd MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Myh6-Tnnt2*R92Q)1Lnwd
transgene insertion 1, Leslie A Leinwand
MGI:3692448

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-Tnnt2*R92Q)1Lnwd/0	involves: C57BL/6	MGI:5755251

Allelic Composition	Tg(Myh6-Tnnt2*R92Q)1Lnwd/0
Genetic Background	involves: C57BL/6

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Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart atrium morphology ( J:56911 )

• progressive atrial hypertrophy

cardiac hypertrophy ( J:56911 )

• progressive atrial hypertrophy

• hearts exhibit expression of hypertrophic markers

• ventricular mass decreases by about 18%

muscle

abnormal sarcomere morphology ( J:56911 )

• sarcomere lengths are shorter in left ventricular myocytes

growth/size/body

cardiac hypertrophy ( J:56911 )

• progressive atrial hypertrophy

• hearts exhibit expression of hypertrophic markers

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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