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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gabpatm1.1Sjb
targeted mutation 1.1, Steven J Burden
MGI:3665313
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gabpatm1.1Sjb/Gabpatm1.1Sjb involves: 129S6/SvEvTac * C57BL/6 MGI:3714844
cn2
 		Gabpatm1Sjb/Gabpatm1.1Sjb
Tg(ACTA1-cre)79Jme/0 		involves: 129S6/SvEvTac * C57BL/6 MGI:3714846


Genotype
MGI:3714844
hm1
Allelic
Composition		 Gabpatm1.1Sjb/Gabpatm1.1Sjb
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabpatm1.1Sjb mutation (0 available); any Gabpa mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:121823 )
• homozygous embryos die and are resorbed prior to E8.5




Genotype
MGI:3714846
cn2
Allelic
Composition		 Gabpatm1Sjb/Gabpatm1.1Sjb
Tg(ACTA1-cre)79Jme/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabpatm1.1Sjb mutation (0 available); any Gabpa mutation (66 available)
Gabpatm1Sjb mutation (0 available); any Gabpa mutation (66 available)
Tg(ACTA1-cre)79Jme mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:121823 )
• mice do not exhibit any muscular or motor nerve defects; neuromuscular synapses form normally and acetycholine receptor clusters are present; transcription from synaptic nuclei also appears unaffected




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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory