Phenotypes associated with this allele

• Allele Symbol: Igh-V7183^tm1Cgn
• Allele Name: targeted mutation 1, University of Cologne
• Allele ID: MGI:3665278
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Igh-V7183^tm1Cgn/Igh-V7183^tm1Cgn	either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)	MGI:3690931

Genotype
MGI:3690931

hm1

• Allelic Composition: Igh-V7183^tm1Cgn/Igh-V7183^tm1Cgn
• Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:112978 )

N • B cell development and physiology as well as B and T cell composition of the bone marrow and spleen, peritoneal B cell populations, and IgM and IgG serum concentrations are all similar to wild-type mice

N • however, the pattern of V7183 gene rearrangements is abnormal