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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dmpktm2Bew
targeted mutation 2, Be Wieringa
MGI:3665271
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dmpktm2Bew/Dmpktm2Bew involves: 129P2/OlaHsd * C57BL/6 MGI:3690767
ht2
 		Dmpktm2Bew/Dmpk+ involves: 129P2/OlaHsd * C3H * C57BL/6 MGI:3690768


Genotype
MGI:3690767
hm1
Allelic
Composition		 Dmpktm2Bew/Dmpktm2Bew
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmpktm2Bew mutation (0 available); any Dmpk mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:113264 )
• viable and fertile with no overt abnormalities and the number of repeats is essentially stable between generations although somatic repeat expansion is seen particularly in the stomach, kidney, and small intestine




Genotype
MGI:3690768
ht2
Allelic
Composition		 Dmpktm2Bew/Dmpk+
Genetic
Background		 involves: 129P2/OlaHsd * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmpktm2Bew mutation (0 available); any Dmpk mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:113264 )
• viable and fertile with no overt abnormalities but the number of repeats may become unstable, with one lineage showing slow but progressive increments in repeat size over successive generations
• somatic repeat expansion is also greater in mice with more than 50% C3H in their strain background




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory