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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jak3X887Y
X887Y
MGI:3665252
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Jak3X887Y/Jak3X887Y Not Specified MGI:3691009
cx2
 		Jak3X887Y/Jak3X887Y
Trdctm1Mal/Trdctm1Mal 		involves: C57BL/6 MGI:3690998


Genotype
MGI:3691009
hm1
Allelic
Composition		 Jak3X887Y/Jak3X887Y
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak3X887Y mutation (0 available); any Jak3 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal hematopoietic system morphology/development ( J:112658 )
• authors state that phenotype is similar to published Jak3-null mice

immune system

endocrine/exocrine glands




Genotype
MGI:3690998
cx2
Allelic
Composition		 Jak3X887Y/Jak3X887Y
Trdctm1Mal/Trdctm1Mal
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak3X887Y mutation (0 available); any Jak3 mutation (85 available)
Trdctm1Mal mutation (1 available); any Trdc mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:112658 )
N
• Tcrd locus transcription is unaffected in Jak3-deficient mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory