Analysis Tools
mortality/aging
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• very few males survive to birth and none survive for more than 1 to 2 days
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Allele Symbol Allele Name Allele ID |
Tg(Myh6-Lef1)2Tfo transgene insertion 2, Thomas Force MGI:3664022 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• very few males survive to birth and none survive for more than 1 to 2 days
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• left ventricular posterior wall thickness is reduced by an average of 22%
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• ventricles are dilated with depressed contractile function, consistent with severe dilated cardiomyopathy
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• cardiomyocytes exhibit limited ability to undergo concentric hypertrophy
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• ventricles are dilated with depressed contractile function, consistent with severe dilated cardiomyopathy
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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