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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rfngtm2.1Tfv
targeted mutation 2.1, Thomas F Vogt
MGI:3662622
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rfngtm2.1Tfv/Rfngtm2.1Tfv involves: 129P2/OlaHsd * 129S6/SvEvTac MGI:3663789
hm2
 		Rfngtm2.1Tfv/Rfngtm2.1Tfv involves: FVB/N MGI:3663788


Genotype
MGI:3663789
hm1
Allelic
Composition		 Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rfngtm2.1Tfv mutation (0 available); any Rfng mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:110952 )
• removal of PGK neo cassette from Rfngtm2 by microinjection of a circularized Cre recombinase-expressing plasmid into Rfngtm2 heterozygote fertilized eggs and subsequent crossing resulted in homozygous mice which are viable and morphologically normal




Genotype
MGI:3663788
hm2
Allelic
Composition		 Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rfngtm2.1Tfv mutation (0 available); any Rfng mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:110952 )
• removal of PGK neo cassette from Rfngtm2 by crossing with Cre expressing "deleter" mice resulted in homozygous mice which are viable and morphologically normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory