Phenotypes associated with this allele

• Allele Symbol: Col6a5⁺
• Allele Name: wild type
• Allele ID: MGI:3660843
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Col6a5^em1Ics/Col6a5^+	C57BL/6N-Col6a5^em1Ics	MGI:8314394

Genotype
MGI:8314394

ht1

• Allelic Composition: Col6a5^em1Ics/Col6a5⁺
• Genetic Background: C57BL/6N-Col6a5^em1Ics

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

impaired skin barrier function ( J:350811 )

♀ • females, but not males, show increased skin permeability

integument

impaired skin barrier function ( J:350811 )

♀ • females, but not males, show increased skin permeability

increased pruritus ( J:350811 )

• females and males show an increase in the time spent scratching over 6 to 32 weeks

• females and males show an increase in the number of scratching bouts per 30 min