Phenotypes associated with this allele

• Allele Symbol: Chga^tm1Gnh
• Allele Name: targeted mutation 1, Geoffrey N Hendy
• Allele ID: MGI:3653689
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chga^tm1Gnh/Chga^tm1Gnh	involves: 129S1/Sv * 129X1/SvJ * BALB/c	MGI:3653864

Genotype
MGI:3653864

hm1

• Allelic Composition: Chga^tm1Gnh/Chga^tm1Gnh
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal urine catecholamine level ( J:111025 )

• elevated urine levels of epinephrine, norepinephrine, and dopamine

• however; renal and hepatic function are similar to wild-type

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:111025 )

N • gross adrenal gland morphology and microscopic structure of epinephrine and norepinephrine storing cells are similar to wild-type

N • endocrine gland function and secretory function of the sympathetic nervous system, somatotrophs, and gonadotrophs are not different from wild-type

reproductive system

reproductive system phenotype ( J:111025 )

N • males and females are fertile and produce normal sized litters

homeostasis/metabolism

abnormal urine catecholamine level ( J:111025 )

• elevated urine levels of epinephrine, norepinephrine, and dopamine

• however; renal and hepatic function are similar to wild-type