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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptentm2Hwu
targeted mutation 2, Hong Wu
MGI:3653409
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ptentm2Hwu/Pten+ involves: 129S4/SvJae * BALB/c MGI:3707124
ht2
 		Ptentm2Hwu/Pten+ involves: 129S4/SvJae * C57BL/6 MGI:3707125


Genotype
MGI:3707124
ht1
Allelic
Composition		 Ptentm2Hwu/Pten+
Genetic
Background		 involves: 129S4/SvJae * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm2Hwu mutation (0 available); any Pten mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
abnormal tumor incidence ( J:110567 )
• Background Sensitivity: spectrum of tumor incidence and onset on the BALB/c background are similar to Ptentm1.1Hwu on the BALB/c background in the first seven months




Genotype
MGI:3707125
ht2
Allelic
Composition		 Ptentm2Hwu/Pten+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm2Hwu mutation (0 available); any Pten mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
abnormal tumor incidence ( J:110567 )
• Background Sensitivity: tumor incidence is about 9-fold higher on C57BL/6 background than on 129/BALB/c background




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory