Phenotypes associated with this allele

• Allele Symbol: Ocln^tm1Tshi
• Allele Name: targeted mutation 1, Takashi Shinohara
• Allele ID: MGI:3641043
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ocln^tm1Tshi/Ocln^tm1Tshi	involves: C57BL/6 * DBA/2	MGI:3641045

Genotype
MGI:3641045

hm1

• Allelic Composition: Ocln^tm1Tshi/Ocln^tm1Tshi
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal salivary gland duct morphology ( J:110222 )

• the striated ducts cells lack characteristic cytoplasmic granules

abnormal stomach mucosa morphology ( J:110222 )

• consists mostly of regenerating foveolar cells with infiltrating neutrophils and lymphocytes

abnormal gastric chief cell morphology ( J:110222 )

• marked decrease in the number of chief cells

abnormal gastric parietal cell morphology ( J:110222 )

• marked decrease in the number of parietal cells

abnormal stomach muscularis externa morphology ( J:110222 )

• degeneration of the proper muscle of the stomach

stomach inflammation ( J:110222 )

• chronic gastritis

skeleton

abnormal trabecular bone morphology ( J:110222 )

• decreased thickness of the trabecular bone of the femur

muscle

abnormal muscle morphology ( J:110222 )

• degeneration of the proper muscle of the stomach

abnormal stomach muscularis externa morphology ( J:110222 )

• degeneration of the proper muscle of the stomach

endocrine/exocrine glands

abnormal salivary gland duct morphology ( J:110222 )

• the striated ducts cells lack characteristic cytoplasmic granules

abnormal gastric chief cell morphology ( J:110222 )

• marked decrease in the number of chief cells

abnormal gastric parietal cell morphology ( J:110222 )

• marked decrease in the number of parietal cells

immune system

stomach inflammation ( J:110222 )

• chronic gastritis