Phenotypes associated with this allele

• Allele Symbol: Ednrb^tm1Myks
• Allele Name: targeted mutation 1, Myung K Shin
• Allele ID: MGI:3640402
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ednrb^tm1Myks/Ednrb^tm1Myks	involves: 129P2/OlaHsd	MGI:3640501

Genotype
MGI:3640501

hm1

• Allelic Composition: Ednrb^tm1Myks/Ednrb^tm1Myks
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:84057 )

• homozygotes die as juveniles from megacolon

cellular

abnormal cell migration ( J:84057 )

• melanocyte migration is delayed and at appears to be arrested at the dorsal end of the dermomyotome at E11.5

digestive/alimentary system

megacolon ( J:84057 )

• homozygotes display megacolon as juveniles

pigmentation

absent coat pigmentation ( J:84057 )

• homozygotes are almost completely white with pigmented areas in the head and rump regions

integument

absent coat pigmentation ( J:84057 )

• homozygotes are almost completely white with pigmented areas in the head and rump regions