cardiovascular system
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• hearts display increased left ventricular end systolic and left ventricular end diastolic diameters, indicating ventricular dilation
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• 8 week old mutants show decreased heart contractility as evidenced by reduced fractional shortening, however show no alteration in anterior and posterior wall thickness or in left ventricular mass
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muscle
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• 8 week old mutants show decreased heart contractility as evidenced by reduced fractional shortening, however show no alteration in anterior and posterior wall thickness or in left ventricular mass
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Analysis Tools