All Phenotypes Tg(Krt10-cre/ERT2)1Pcn MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Krt10-cre/ERT2)1Pcn
transgene insertion 1, Pierre Chambon
MGI:3629075

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pparg^tm1.2Mtz/Pparg^tm1.2Mtz Tg(Krt10-cre/ERT2)1Pcn/0	involves: C57BL/6 * SJL	MGI:3629416

Allelic Composition	Pparg^tm1.2Mtz/Pparg^tm1.2Mtz Tg(Krt10-cre/ERT2)1Pcn/0
Genetic Background	involves: C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pparg^tm1.2Mtz mutation (0 available); any Pparg mutation (39 available)
Tg(Krt10-cre/ERT2)1Pcn mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal skin morphology ( J:109090 )

• phenotype of adult mutant epidermis is similar to that observed in Rxr- and Rar-conditional knockouts

abnormal keratinocyte morphology ( J:109090 )

• granular keratinocytes in mutants contain vesicles devoid of lamellae or with disorganized lamellae

• disorganized lamellae form aggregates at the apical pole of granular keratinocytes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23