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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Penktm1Jep
targeted mutation 1, John E Pintar
MGI:3628668
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Penktm1Jep/Penktm1Jep involves: 129S/SvEv * C57BL/6J MGI:3639144


Genotype
MGI:3639144
hm1
Allelic
Composition		 Penktm1Jep/Penktm1Jep
Genetic
Background		 involves: 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Penktm1Jep mutation (0 available); any Penk mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal behavioral response to addictive substance ( J:109209 )
• compared to control, no significant differences in the global withdrawal score under the same chronic treatment of morphine
• develop a level of physical dependence that is at least comparable with that of wild-type mice control
abnormal chemically-elicited antinociception ( J:109209 )
• do not develop analgesic tolerance to morphine




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory