About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lingo1tm1Shmi
targeted mutation 1, Sha Mi
MGI:3623893
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lingo1tm1Shmi/Lingo1tm1Shmi involves: 129S2/SvPas * C57BL/6 MGI:3624261


Genotype
MGI:3624261
hm1
Allelic
Composition		 Lingo1tm1Shmi/Lingo1tm1Shmi
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lingo1tm1Shmi mutation (0 available); any Lingo1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelination ( J:99078 )
• onset of myelination in the CNS of mutants is earlier than in wild-type; P1 spinal cords from mutants have more myelinated axon fibers than wild-type controls; oligodendrocytes cultured from mutants are more highly differentiated when cultured and more mature oligodendrocytes are observed in mutant cultures




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory