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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dync2h1Gt(RRM278)Byg
gene trap RRM278, BayGenomics
MGI:3623884
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dync2h1Gt(RRM278)Byg/Dync2h1Gt(RRM278)Byg involves: 129P2/OlaHsd MGI:3624274
ht2
 		Dync2h1Gt(RRM278)Byg/Dync2h1lln involves: 129P2/OlaHsd * C57BL/6J MGI:3624273


Genotype
MGI:3624274
hm1
Allelic
Composition		 Dync2h1Gt(RRM278)Byg/Dync2h1Gt(RRM278)Byg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1Gt(RRM278)Byg mutation (0 available); any Dync2h1 mutation (214 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
abnormal direction of heart looping ( J:100466 )
• mutants exhibit randomization of heart looping polarity

nervous system




Genotype
MGI:3624273
ht2
Allelic
Composition		 Dync2h1Gt(RRM278)Byg/Dync2h1lln
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1Gt(RRM278)Byg mutation (0 available); any Dync2h1 mutation (214 available)
Dync2h1lln mutation (0 available); any Dync2h1 mutation (214 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
abnormal direction of heart looping ( J:100466 )
• mutants exhibit randomization of heart looping polarity

nervous system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory