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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo
targeted mutation 3, Liqun Luo
MGI:3623347
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo involves: 129S1/Sv * 129X1/SvJ MGI:3665429
cn2
 		Dscamtm1Pfu/Dscamtm1Pfu
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/?
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:5305036


Genotype
MGI:3665429
hm1
Allelic
Composition		 Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (1046 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:113339 )
• homozygotes diaplay some lethality

reproductive system
reduced fertility ( J:113339 )
• homoygotes have low fertility; heterozygotes show no fertility defects




Genotype
MGI:5305036
cn2
Allelic
Composition		 Dscamtm1Pfu/Dscamtm1Pfu
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/?
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dscamtm1Pfu mutation (1 available); any Dscam mutation (107 available)
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (1046 available)
Tg(Chx10-EGFP/cre,-ALPP)2Clc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal amacrine cell morphology ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

nervous system
abnormal axon fasciculation ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped
abnormal amacrine cell morphology ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

cellular
abnormal axon fasciculation ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory