About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo
targeted mutation 3, Liqun Luo
MGI:3623347
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo involves: 129S1/Sv * 129X1/SvJ MGI:3665429
cn2
 		Dscamtm1Pfu/Dscamtm1Pfu
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/?
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:5305036


Genotype
MGI:3665429
hm1
Allelic
Composition		 Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (942 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:113339 )
• homozygotes diaplay some lethality

reproductive system
reduced fertility ( J:113339 )
• homoygotes have low fertility; heterozygotes show no fertility defects




Genotype
MGI:5305036
cn2
Allelic
Composition		 Dscamtm1Pfu/Dscamtm1Pfu
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/?
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dscamtm1Pfu mutation (1 available); any Dscam mutation (105 available)
Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (942 available)
Tg(Chx10-EGFP/cre,-ALPP)2Clc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal amacrine cell morphology ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

nervous system
abnormal axon fasciculation ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped
abnormal amacrine cell morphology ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped

cellular
abnormal axon fasciculation ( J:179393 )
• recombined but not non-recombined dopaminergic amacrine cells and neurites are clumped




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory