Phenotypes associated with this allele

• Allele Symbol: T2dm2sa^A/JNshm
• Allele Name: A/JNshm
• Allele ID: MGI:3622825
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	T2dm2sa^A/JNshm/T2dm2sa^A/JNshm	involves: SM.A-(D2Mit295-D2Mit281)	MGI:3622827
hm2	T2dm2sa^A/JNshm/T2dm2sa^A/JNshm	involves: SM/J * SMXA5	MGI:3622826

Genotype
MGI:3622827

hm1

• Allelic Composition: T2dm2sa^A/JNshm/T2dm2sa^A/JNshm
• Genetic Background: involves: SM.A-(D2Mit295-D2Mit281)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating glucose level ( J:107889 )

• increased fasting and free-fed blood glucose

increased circulating insulin level ( J:107889 )

• increased free-fed insulin concentration

adipose tissue

increased total body fat amount ( J:107889 )

• increased subcutaneous and mesenteric fat weight percentage

growth/size/body

increased body mass index ( J:107889 )

increased body weight ( J:107889 )

Genotype
MGI:3622826

hm2

• Allelic Composition: T2dm2sa^A/JNshm/T2dm2sa^A/JNshm
• Genetic Background: involves: SM/J * SMXA5

homeostasis/metabolism

increased circulating glucose level ( J:107889 )

• increased free-fed blood glucose

increased circulating insulin level ( J:107889 )

• increased fasting insulin

impaired glucose tolerance ( J:107889 )

• impaired glucose tolerance at all time points in IPGTT