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Allele Symbol Allele Name Allele ID |
Tg(MMTV-Myc)#Led transgene insertion, Philip Leder MGI:3621200 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• while tumor latency, multiplicity and growth rate are similar to controls, the fraction of mice with lung metastases is about 5 fold lower compared to transgenic mice wild-type for Hunk
• a decrease in metastases is also seen when primary tumors are transplanted in nude mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• while tumor latency, multiplicity and growth rate are similar to controls, the fraction of mice with lung metastases is reduced compared to transgenic mice wild-type for Hunk but increased compared to transgenic mice that are homozygous for the mutant allele
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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