Phenotypes associated with this allele

• Allele Symbol: Maml1^tm1Lizw
• Allele Name: targeted mutation 1, Lizi Wu
• Allele ID: MGI:3621180
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Maml1^tm1Lizw/Maml1^tm1Lizw	involves: 129	MGI:3621457

Genotype
MGI:3621457

hm1

• Allelic Composition: Maml1^tm1Lizw/Maml1^tm1Lizw
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:106711 )

• die within 10 days of birth

growth/size/body

decreased body size ( J:106711 )

• remain smaller after birth

fetal growth retardation ( J:106711 )

• delayed growth visible at birth

muscle

skeletal muscle fiber necrosis ( J:106711 )

• degeneration and necrosis of some but not all myofibers

increased variability of skeletal muscle fiber size ( J:106711 )

• variable myofiber size (atrophic and hypertrophic)

cellular

skeletal muscle fiber necrosis ( J:106711 )

• degeneration and necrosis of some but not all myofibers