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Allele Symbol Allele Name Allele ID |
917M 917M MGI:3620956 |
| Summary |
2 genotypes |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• basal and shear-stress stimulated proliferation are reduced in male heterozygotes, but not female heterozygotes
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• bone area, mineral content, cortical area, periosteal circumference and endosteal circumference at the midshaft of the tibia are reduced; however, length is similar to wild-type
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• total body bone area is decreased
(J:132290)
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• total body bone area and weight adjusted bone area are reduced in male heterozygotes by 10-13% and 9-10%, respectively, compared to wild-type
(J:99483)
• however, bone area and mineral content in female heterozygotes are similar to wild-type
(J:99483)
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• bone mineral content, but not bone mineral density, is reduced in male heterozygotes
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• bone area, mineral content, cortical area, periosteal circumference and endosteal circumference at the midshaft of the tibia are reduced; however, length is similar to wild-type
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• basal and shear-stress stimulated proliferation are reduced in male heterozygotes, but not female heterozygotes
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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