Phenotypes associated with this allele

• Allele Symbol: Abraxas1⁺
• Allele Name: wild type
• Allele ID: MGI:3619975
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Abraxas1^tm1.1Bwng/Abraxas1^+	involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N	MGI:6296797

Genotype
MGI:6296797

ht1

• Allelic Composition: Abraxas1^tm1.1Bwng/Abraxas1⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:269823 )

• nearly all mice are dead by 30 months of age

neoplasm

increased tumor incidence ( J:269823 )

• mice develop cancer including lymphoma and other types of tumors (lung, liver and other)

• mice develop tumors as early as 8 months with a mean age of 17 months

increased lymphoma incidence ( J:269823 )

• in 14 of 21 mice with involvement in the spleen and lymph nodes including the mesenteric and cervical lymph nodes and infiltration into the liver, lung, kidney and intestine

increased histiocytic sarcoma incidence ( J:269823 )

• in one mouse

increased lung adenocarcinoma incidence ( J:269823 )

• in one mouse

respiratory system

increased lung adenocarcinoma incidence ( J:269823 )

• in one mouse