All Phenotypes B4galnt2<tm1Jbl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

B4galnt2^tm1Jbl
targeted mutation 1, John B Lowe
MGI:3618460

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	B4galnt2^tm1Jbl/B4galnt2^tm1Jbl	involves: 129S1/Sv	MGI:3714972

Allelic Composition	B4galnt2^tm1Jbl/B4galnt2^tm1Jbl
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B4galnt2^tm1Jbl mutation (0 available); any B4galnt2 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased neutrophil cell number ( J:217719 )

abnormal B cell number ( J:217719 )

• increase in Gr-1, CD138 B cells

• decrease in CD3, CD62L, CD22+ B cells

cardiovascular system

increased systemic arterial diastolic blood pressure ( J:217719 )

behavior/neurological

increased startle reflex ( J:217719 )

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:217719 )

hematopoietic system

increased neutrophil cell number ( J:217719 )

abnormal B cell number ( J:217719 )

• increase in Gr-1, CD138 B cells

• decrease in CD3, CD62L, CD22+ B cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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