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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr70tm1Alb
targeted mutation 4, Arthur L Beaudet
MGI:3617404
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr70tm1Alb/Rr70tm1Alb involves: 129S7/SvEvBrd * C57BL/6 MGI:3717483
ht2
 		Rr70tm1Alb/Rr70+ involves: 129S7/SvEvBrd * C57BL/6J MGI:3719122
cx3
 		Arid4atm1Alb/Arid4atm1Alb
Rr70tm1Alb/Rr70+ 		involves: 129S7/SvEvBrd * C57BL/6 MGI:3717482
cx4
 		Arid4btm1Alb/Arid4b+
Rr70tm1Alb/Rr70+ 		involves: 129S7/SvEvBrd * C57BL/6 MGI:3717489
cx5
 		Rb1tm1Brd/Rb1+
Rr70tm1Alb/Rr70+ 		involves: 129S7/SvEvBrd * C57BL/6 MGI:3717490
cx6
 		Rr70tm1Alb/Rr70+
Snrpntm2Alb/Snrpn+ 		involves: 129S7/SvEvBrd * C57BL/6J MGI:3719123


Genotype
MGI:3717483
hm1
Allelic
Composition		 Rr70tm1Alb/Rr70tm1Alb
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:113402 )
• all mice lack correct DNA methylation patterns




Genotype
MGI:3719122
ht2
Allelic
Composition		 Rr70tm1Alb/Rr70+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
genetic imprinting ( J:105289 )
• when the allele is inherited maternally methylation patterns associated with imprinting are defective
• however, when the allele is inherited paternally methylation associated with imprinting is normal




Genotype
MGI:3717482
cx3
Allelic
Composition		 Arid4atm1Alb/Arid4atm1Alb
Rr70tm1Alb/Rr70+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arid4atm1Alb mutation (0 available); any Arid4a mutation (60 available)
Rr70tm1Alb mutation (0 available); any Rr70 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:113402 )
• 7 of 12 mice lack correct DNA methylation patterns




Genotype
MGI:3717489
cx4
Allelic
Composition		 Arid4btm1Alb/Arid4b+
Rr70tm1Alb/Rr70+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arid4btm1Alb mutation (0 available); any Arid4b mutation (65 available)
Rr70tm1Alb mutation (0 available); any Rr70 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:113402 )
• 14 of 18 mice lack correct DNA methylation patterns




Genotype
MGI:3717490
cx5
Allelic
Composition		 Rb1tm1Brd/Rb1+
Rr70tm1Alb/Rr70+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm1Brd mutation (0 available); any Rb1 mutation (106 available)
Rr70tm1Alb mutation (0 available); any Rr70 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal imprinting ( J:113402 )
• 7 of 10 mice lack correct DNA methylation patterns




Genotype
MGI:3719123
cx6
Allelic
Composition		 Rr70tm1Alb/Rr70+
Snrpntm2Alb/Snrpn+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr70tm1Alb mutation (0 available); any Rr70 mutation (0 available)
Snrpntm2Alb mutation (0 available); any Snrpn mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
growth/size/body region phenotype ( J:105289 )
N
• mice have normal weights and growth rates even when the Snrpntm2Alb allele is inherited paternally




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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory