Phenotypes associated with this allele

• Allele Symbol: Snai1^tm2.1Grid
• Allele Name: targeted mutation 2.1, Tom Gridley
• Allele ID: MGI:3617388
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Snai1^tm2.1Grid/Snai1^tm2.1Grid	involves: 129S1/Sv * C57BL/6J	MGI:3618123
ht2	Snai1^tm1Grid/Snai1^tm2.1Grid	involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J	MGI:3618120

Genotype
MGI:3618123

hm1

• Allelic Composition: Snai1^tm2.1Grid/Snai1^tm2.1Grid
• Genetic Background: involves: 129S1/Sv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:105294 )

• development arrests at gastrulation with mesodermal defects being observed

embryo

abnormal mesoderm development ( J:105294 )

• embryos develop lacunae within the mesodermal wings, bounded by mesodermal cells exhibiting the morphology of a polarized, columnar epithelium

embryonic growth arrest ( J:105294 )

• embryo development is arrested at gastrulation

Genotype
MGI:3618120

ht2

• Allelic Composition: Snai1^tm1Grid/Snai1^tm2.1Grid
• Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J

embryo

abnormal mesoderm development ( J:105294 )

• embryos develop lacunae within the mesodermal wings, bounded by mesodermal cells exhibiting the morphology of a polarized, columnar epithelium