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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sema3btm1Cast
targeted mutation 1, Valerie Castellani
MGI:3617382
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sema3btm1Cast/Sema3btm1Cast involves: 129S1/Sv * 129X1/SvJ * C57BL/6A MGI:3618111
ht2
 		Sema3btm1Cast/Sema3b+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6A MGI:3618113


Genotype
MGI:3618111
hm1
Allelic
Composition		 Sema3btm1Cast/Sema3btm1Cast
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6A
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema3btm1Cast mutation (0 available); any Sema3b mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased anterior commissure size ( J:105299 )
• the anterior commissure is expanded ventrally by 82% compared to wild-type




Genotype
MGI:3618113
ht2
Allelic
Composition		 Sema3btm1Cast/Sema3b+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6A
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema3btm1Cast mutation (0 available); any Sema3b mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased anterior commissure size ( J:105299 )
• anterior commissure is expanded ventrally by 41% in heterozygotes compared to wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory