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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppardtm2Rev
targeted mutation 2, Ronald M Evans
MGI:3616172
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppardtm2Rev/Ppardtm2Rev involves: 129S4/SvJae MGI:3715728


Genotype
MGI:3715728
hm1
Allelic
Composition		 Ppardtm2Rev/Ppardtm2Rev
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppardtm2Rev mutation (1 available); any Ppard mutation (68 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:105694 )
• homozygous embryos die in utero

embryo
abnormal extraembryonic tissue morphology ( J:105694 )
• embryonic phenotype is stated to be similar, albeit earlier, to that of Ppardtm1.1Rev homozygotes; however no data is presented




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory