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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		+
wild type
MGI:3614992
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Del(11Irf1-D11Mit23)1Rub/+ 129/Sv-Del(11Irf1-D11Mit23)1Rub MGI:3614993


Genotype
MGI:3614993
ht1
Allelic
Composition		 Del(11Irf1-D11Mit23)1Rub/+
Genetic
Background		 129/Sv-Del(11Irf1-D11Mit23)1Rub
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(11Irf1-D11Mit23)1Rub mutation (1 available); any Del(11Irf1-D11Mit23)1Rub mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating carnitine level ( J:60187 )
• carnitine levels are reduced by about 20-25% in plasma of deletion hemizygotes relative to wild-type mice
increased circulating VLDL triglyceride level ( J:60187 )
• timed plasma triglyceride measurements under conditions of impaired lipolysis and VLDL triglyceride clearance demonstrate approximately twice the wild-type rate of hepatic VLDL triglyceride secretion in hemizygous deletant mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory