Phenotypes associated with this allele

• Allele Symbol: snthr2
• Allele Name: scanty hair 2
• Allele ID: MGI:3613603
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	snthr2/snthr2	(C57BL/6 x DBA/2)F2	MGI:3613610
hm2	snthr2/snthr2	involves: DBA/2	MGI:3613607

Genotype
MGI:3613610

hm1

• Allelic Composition: snthr2/snthr2
• Genetic Background: (C57BL/6 x DBA/2)F2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

sparse hair ( J:94345 )

• variable penetrance with some exhibiting almost no hair, some exhibiting sparser hair on the back and ventrum, and some exhibiting nearly normal hair density but with a coarse and lusterless texture

• no hair is present on the tail

wrinkled skin ( J:94345 )

• obvious skin wrinkles on mice younger than 4 weeks of age

Genotype
MGI:3613607

hm2

• Allelic Composition: snthr2/snthr2
• Genetic Background: involves: DBA/2

growth/size/body

postnatal growth retardation ( J:94345 )

• young mice grow more slowly than controls, but no differences in body size are seen in adult mice

behavior/neurological

abnormal nursing ( J:94345 )

♀ • a defect in feeding and nursing ability is seen in females

integument

sparse hair ( J:94345 )

• coat shows scant hair

decreased hair follicle number ( J:94345 )

• at 4.5 days of age, hair follicle number and arrangement appears normal

• at 2 months of age, a reduced number of hair follicles are present and some exhibit keratosis

hyperkeratosis ( J:94345 )

• hyperkeratosis of the epidermis is apparent at 2 months of age

wrinkled skin ( J:94345 )

• obvious skin wrinkles appear 3-4 days after birth