Phenotypes associated with this allele

• Allele Symbol: Srpk3^tm1Eno
• Allele Name: targeted mutation 1, Eric N Olson
• Allele ID: MGI:3613582
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srpk3^tm1Eno/Srpk3^tm1Eno	either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J)	MGI:3613583
ot2	Srpk3^tm1Eno/Y	either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J)	MGI:3613589

Genotype
MGI:3613583

hm1

• Allelic Composition: Srpk3^tm1Eno/Srpk3^tm1Eno
• Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal skeletal muscle morphology ( J:100494 )

♀ • defects include a disorganized myofibrillar network

♀ • no evidence of regenerative markers, inflammation, fibrosis or apoptosis, or defects in sarcolemmal integrity

centrally nucleated skeletal muscle fibers ( J:100494 )

♀ • centrally placed nuclei are observed in type 2 muscle fibers

decreased skeletal muscle mass ( J:100494 )

♀ • defects in skeletal muscle growth are indicated by significantly reduced mass of various skeletal muscle groups

Genotype
MGI:3613589

ot2

• Allelic Composition: Srpk3^tm1Eno/Y
• Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J)

muscle

abnormal skeletal muscle morphology ( J:100494 )

♂ • defects include a disorganized myofibrillar network

♂ • no evidence of regenerative markers, inflammation, fibrosis or apoptosis, or defects in sarcolemmal integrity

centrally nucleated skeletal muscle fibers ( J:100494 )

♂ • centrally placed nuclei are observed in type 2 muscle fibers

decreased skeletal muscle mass ( J:100494 )

♂ • defects in skeletal muscle growth are indicated by significantly reduced mass of various skeletal muscle groups