About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cntn6tm1Kwat
targeted mutation 1, Kazutada Watanabe
MGI:3613462
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cntn6tm1Kwat/Cntn6tm1Kwat involves: 129X1/SvJ * C57BL/6 MGI:3613527
ht2
Cntn6tm1Kwat/Cntn6+ involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 MGI:3820311
cx3
Chl1tm1Mtg/Chl1+
Cntn6tm1Kwat/Cntn6+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 MGI:3820310
cx4
Cntn6tm1Kwat/Cntn6tm1Kwat
Tg(Thy1-YFP)HJrs/0
involves: 129X1/SvJ * C57BL/6 * CBA MGI:3820309


Genotype
MGI:3613527
hm1
Allelic
Composition
Cntn6tm1Kwat/Cntn6tm1Kwat
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntn6tm1Kwat mutation (1 available); any Cntn6 mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• brain size as well as body size normal
• brain cytoarchitecture normal
• normal excitatory synaptic function in the cerebellum

behavior/neurological
• as measured in a rotarod test, a stationary horizontal balance rod, and hanging wire test




Genotype
MGI:3820311
ht2
Allelic
Composition
Cntn6tm1Kwat/Cntn6+
Genetic
Background
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntn6tm1Kwat mutation (1 available); any Cntn6 mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants exhibit misorientation of apical dendrites in layer V pyramidal neurons in the visual cortex




Genotype
MGI:3820310
cx3
Allelic
Composition
Chl1tm1Mtg/Chl1+
Cntn6tm1Kwat/Cntn6+
Genetic
Background
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chl1tm1Mtg mutation (0 available); any Chl1 mutation (56 available)
Cntn6tm1Kwat mutation (1 available); any Cntn6 mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants exhibit a more severe misorientation of apical dendrites in layer V pyramidal neurons in the visual cortex than seen in either heterozygous mouse




Genotype
MGI:3820309
cx4
Allelic
Composition
Cntn6tm1Kwat/Cntn6tm1Kwat
Tg(Thy1-YFP)HJrs/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntn6tm1Kwat mutation (1 available); any Cntn6 mutation (63 available)
Tg(Thy1-YFP)HJrs mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants exhibit misorientation of apical dendrites in layer V pyramidal neurons in the visual cortex, but not in motor, somatosensory, or auditory cortices or in the upper layer of the visual cortex





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory