Phenotypes associated with this allele

• Allele Symbol: sky
• Allele Name: severe kyphosis
• Allele ID: MGI:3612272
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	sky/sky	DBA/2J-sky/J	MGI:3797383

Genotype
MGI:3797383

hm1

• Allelic Composition: sky/sky
• Genetic Background: DBA/2J-sky/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:136875 )

• homozygotes die between 3 and 6 months of age

skeleton

abnormal caudal vertebrae morphology ( J:136875 )

• the tail appears to be in a higher than normal position due to the kyphosis

abnormal intervertebral disk morphology ( J:136875 )

• degeneration of articular cartilage and foci of periarticular carticular necrosis

intervertebral disk degeneration ( J:136875 )

kyphosis ( J:136875 )

• progressive S-shaped kyphosis of the lumbar region that becomes severe

limbs/digits/tail

abnormal caudal vertebrae morphology ( J:136875 )

• the tail appears to be in a higher than normal position due to the kyphosis

vision/eye

eyelids open at birth ( J:136875 )

adipose tissue

abnormal adipose tissue morphology ( J:136875 )

• small granulomas in brown fat and foci of fat necrosis

abnormal brown adipose tissue morphology ( J:136875 )

muscle

abnormal muscle morphology ( J:136875 )

• small granulomas in muscle

growth/size/body

decreased body length ( J:136875 )

• shortened trunk due to the kyphosis

reproductive system

abnormal fertility/fecundity ( J:136875 )

• homozygotes do not breed