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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdkn1btm2Jro
targeted mutation 2, James M Roberts
MGI:3611831
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdkn1btm2Jro/Cdkn1btm2Jro involves: 129S4/SvJaeSor * C57BL/6 MGI:3613029


Genotype
MGI:3613029
hm1
Allelic
Composition		 Cdkn1btm2Jro/Cdkn1btm2Jro
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1btm2Jro mutation (1 available); any Cdkn1b mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:103819 )
• develop fewer urethane-induced lung tumors and have fewer number of large tumors, indicating decreased growth rate of tumors, than heterozygous Cdkn1btm1Mif mice

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:103819 )
• develop fewer urethane-induced lung tumors and have fewer number of large tumors, indicating decreased growth rate of tumors, than heterozygous Cdkn1btm1Mif mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory