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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adamts1tm1Mlia
targeted mutation 1, M Luisa Iruela-Arispe
MGI:3609982
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adamts1tm1Mlia/Adamts1tm1Mlia involves: 129X1/SvJ * BALB/c MGI:3610387


Genotype
MGI:3610387
hm1
Allelic
Composition		 Adamts1tm1Mlia/Adamts1tm1Mlia
Genetic
Background		 involves: 129X1/SvJ * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts1tm1Mlia mutation (0 available); any Adamts1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, incomplete penetrance ( J:102464 )
• significant lethality at the intraembryonic/neonatal stage, with about 40% of homozygous null mice not recovered

renal/urinary system
ureter obstruction ( J:102464 )
• display urinary tract obstruction

growth/size/body
decreased body weight ( J:102464 )
• lower weight mass than wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory