Analysis Tools
immune system
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• following sensitization with ovalbumin and exposure to ovalbumin, mice exhibit an 88% increase in cellular inflammatory infiltrate in bronchoalveolar lavage (specifically, total and eosinophil) compared to in similarly treated wild-type mice at 24 hours but not 72 hours post-exposure
• however, cellular composition of the inflammatory infiltrate is normal and IgE levels are normal
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• ovalbumin-induced airway hypersensitivity to methacholine is greater than in similarly treated wild-type mice (57% increase at 20 ug/ml and 52% at 40 ug/ml methacholine)
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respiratory system
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• ovalbumin-induced airway hypersensitivity to methacholine is greater than in similarly treated wild-type mice (57% increase at 20 ug/ml and 52% at 40 ug/ml methacholine)
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