About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppip5k2+
wild type
MGI:3606956
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ppip5k2tm1b(EUCOMM)Wtsi/Ppip5k2+ C57BL/6N-Ppip5k2tm1b(EUCOMM)Wtsi/J MGI:6679102
ht2
 		Ppip5k2tm1a(EUCOMM)Wtsi/Ppip5k2+ involves: C57BL/6N MGI:6198764


Genotype
MGI:6679102
ht1
Allelic
Composition		 Ppip5k2tm1b(EUCOMM)Wtsi/Ppip5k2+
Genetic
Background		 C57BL/6N-Ppip5k2tm1b(EUCOMM)Wtsi/J
Cell Lines EPD0428_7_H01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppip5k2tm1b(EUCOMM)Wtsi mutation (1 available); any Ppip5k2 mutation (75 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological




Genotype
MGI:6198764
ht2
Allelic
Composition		 Ppip5k2tm1a(EUCOMM)Wtsi/Ppip5k2+
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppip5k2tm1a(EUCOMM)Wtsi mutation (1 available); any Ppip5k2 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
cochlear outer hair cell degeneration ( J:260825 )
• at P150 a greater degree of degeneration of OHCs is seen in the basal coil compared to wild-type controls
increased or absent threshold for auditory brainstem response ( J:260825 )
• at P150 the threshold at 24 kHz is significantly increased

nervous system
cochlear outer hair cell degeneration ( J:260825 )
• at P150 a greater degree of degeneration of OHCs is seen in the basal coil compared to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory