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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apctm4Mmt
targeted mutation 4, Makoto M Taketo
MGI:3605472
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apctm4Mmt/Apctm4Mmt B6.129X1-Apctm4Mmt MGI:3606965
ht2
 		Apctm4Mmt/Apc+ B6.129X1-Apctm4Mmt MGI:3606966


Genotype
MGI:3606965
hm1
Allelic
Composition		 Apctm4Mmt/Apctm4Mmt
Genetic
Background		 B6.129X1-Apctm4Mmt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm4Mmt mutation (0 available); any Apc mutation (154 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3606966
ht2
Allelic
Composition		 Apctm4Mmt/Apc+
Genetic
Background		 B6.129X1-Apctm4Mmt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm4Mmt mutation (0 available); any Apc mutation (154 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
intestine polyps ( J:101604 )
• an average of 1.09 polyps per mouse at 15 months of age
increased intestinal adenoma incidence ( J:101604 )
• intesinal polyps are dysplastic adenomas

neoplasm
increased intestinal adenoma incidence ( J:101604 )
• intesinal polyps are dysplastic adenomas




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory