About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mlst8+
wild type
MGI:3605342
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Mlst8tm1Lex/Mlst8+
Ptentm1Rps/Pten+ 		involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6 MGI:4848146


Genotype
MGI:4848146
cx1
Allelic
Composition		 Mlst8tm1Lex/Mlst8+
Ptentm1Rps/Pten+
Genetic
Background		 involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlst8tm1Lex mutation (1 available); any Mlst8 mutation (22 available)
Ptentm1Rps mutation (0 available); any Pten mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
extended life span ( J:144810 )
• double mutants live longer than single heterozygous Pten mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory