Phenotypes associated with this allele

• Allele Symbol: Srd5a3^{Gt(OST436695)Lex}
• Allele Name: gene trap OST436695, Lexicon Genetics
• Allele ID: MGI:3604528
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srd5a3^Gt(OST436695)Lex/Srd5a3^Gt(OST436695)Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609907

Genotype
MGI:3609907

hm1

• Allelic Composition: Srd5a3^{Gt(OST436695)Lex}/Srd5a3^{Gt(OST436695)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:103485 )

• no homozygotes seen at weaning; stage of lethality not specified

embryonic lethality during organogenesis, complete penetrance ( J:163281 )

• mice die between E11.5 and E13.5

embryo

failure of initiation of embryo turning ( J:163281 )

• at E10.5, mice fail to rotate unlike wild-type mice

open neural tube ( J:163281 )

cardiovascular system

dilated heart ( J:163281 )

• at E10.5

nervous system

open neural tube ( J:163281 )

growth/size/body

abnormal ventral body wall morphology ( J:163281 )

• at E10.5