All Phenotypes Scn3a<Gt(OST52130)Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn3a^{Gt(OST52130)Lex}
gene trap OST52130, Lexicon Genetics
MGI:3604522

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scn3a^{Gt(OST52130)Lex}/Scn3a^{Gt(OST52130)Lex}	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609666
ht2	Scn3a^{Gt(OST52130)Lex}/Scn3a⁺	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609668

Allelic Composition	Scn3a^{Gt(OST52130)Lex}/Scn3a^{Gt(OST52130)Lex}
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn3a^{Gt(OST52130)Lex} mutation (1 available); any Scn3a mutation (111 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:103485 )

• greatly reduced viability of homozygotes with only 2 homozygotes detected, one of which died within 3 weeks of birth

growth/size/body

decreased body size ( J:103485 )

behavior/neurological

lethargy ( J:103485 )

Allelic Composition	Scn3a^{Gt(OST52130)Lex}/Scn3a⁺
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn3a^{Gt(OST52130)Lex} mutation (1 available); any Scn3a mutation (111 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

improved glucose tolerance ( J:103485 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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