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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pik3cbGt(OST147188)Lex
gene trap OST147188, Lexicon Genetics
MGI:3604500
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pik3cbGt(OST147188)Lex/Pik3cbGt(OST147188)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609816


Genotype
MGI:3609816
hm1
Allelic
Composition		 Pik3cbGt(OST147188)Lex/Pik3cbGt(OST147188)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3cbGt(OST147188)Lex mutation (2 available); any Pik3cb mutation (149 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:103485 )
• fewer homozygotes than expected are present at weaning, stage of lethality not specified

cardiovascular system
decreased heart rate ( J:103485 )
• decreased mean heart rates are seen in surviving homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory