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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nucb2Gt(OST287865)Lex
gene trap OST287865, Lexicon Genetics
MGI:3604493
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nucb2Gt(OST287865)Lex/Nucb2Gt(OST287865)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609789


Genotype
MGI:3609789
hm1
Allelic
Composition		 Nucb2Gt(OST287865)Lex/Nucb2Gt(OST287865)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nucb2Gt(OST287865)Lex mutation (2 available); any Nucb2 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased heart rate ( J:103485 )
• decreased mean heart rate

homeostasis/metabolism
increased circulating alkaline phosphatase level ( J:103485 )
• increased mean serum alkaline phosphatase levels




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory