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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prnp-MAPT)25Hlmc
transgene insertion 25, Mike Hutton
MGI:3604150
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Prnp-MAPT)25Hlmc/0 involves: C57BL/6 * DBA/2 MGI:3722377


Genotype
MGI:3722377
tg1
Allelic
Composition		 Tg(Prnp-MAPT)25Hlmc/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:63887 )
N
• mice do not display significant motor or behavioral abnormalities up to 10 months of age

nervous system
abnormal brain morphology ( J:63887 )
• tau protein is detected in cortex, hippocampal pyramidal layer, dentate gyrus, and cerebellar dentate nucleus at ~10 months of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory