All Phenotypes repro3 MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

repro3
reproductive mutant 3, JAX Reproductive Mutagenisis Program
MGI:3590190

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	repro3/repro3	involves: C3HeB/FeJ * C57BL/6J	MGI:3697913

Allelic Composition	repro3/repro3
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

oligozoospermia ( J:117563 )

• epididymal sperm concentration is (1.7 +/- 1.7) x 10⁶ sperm/ml

• however, testes and seminal vesicle weights are similar to wild-type

teratozoospermia ( J:117563 )

• all sperm have abnormal head and/or tail morphology

abnormal sperm flagellum morphology ( J:117563 )

• abnormal sperm tail morphology is observed

absent sperm mitochondrial sheath ( J:117563 )

• axonemal profiles lack the associated mitochondrial sheath

short sperm flagellum ( J:117563 )

• sperm tails are short

abnormal sperm head morphology ( J:117563 )

• abnormally shaped sperm heads are observed

abnormal sperm nucleus morphology ( J:117563 )

• abnormal hammerhead nuclear shapes are observed

abnormal spermatid morphology ( J:117563 )

• some spermatids display abnormal hammerhead nuclear shapes and tail elongation is impaired

immotile sperm ( J:117563 )

• immobile sperm

male infertility ( J:117563 )

impaired fertilization ( J:117563 )

• sperm fail to fertilize oocytes in in vitro fertilization tests

cellular

oligozoospermia ( J:117563 )

• epididymal sperm concentration is (1.7 +/- 1.7) x 10⁶ sperm/ml

• however, testes and seminal vesicle weights are similar to wild-type

teratozoospermia ( J:117563 )

• all sperm have abnormal head and/or tail morphology

abnormal sperm flagellum morphology ( J:117563 )

• abnormal sperm tail morphology is observed

absent sperm mitochondrial sheath ( J:117563 )

• axonemal profiles lack the associated mitochondrial sheath

short sperm flagellum ( J:117563 )

• sperm tails are short

abnormal sperm head morphology ( J:117563 )

• abnormally shaped sperm heads are observed

abnormal sperm nucleus morphology ( J:117563 )

• abnormal hammerhead nuclear shapes are observed

abnormal spermatid morphology ( J:117563 )

• some spermatids display abnormal hammerhead nuclear shapes and tail elongation is impaired

immotile sperm ( J:117563 )

• immobile sperm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23