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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Icam1tm1Cws
targeted mutation 1, C Wayne Smith
MGI:3588437
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Icam1tm1Cws/Icam1tm1Cws involves: C57BL/6 MGI:3608598


Genotype
MGI:3608598
hm1
Allelic
Composition		 Icam1tm1Cws/Icam1tm1Cws
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Icam1tm1Cws mutation (0 available); any Icam1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal macrophage morphology ( J:100353 )
• adipose tissue of males has fewer macrophages than wild-type when fed a high fat diet, however weight of fat pads and numbers of adipose lymphocyte do not differ

hematopoietic system
abnormal macrophage morphology ( J:100353 )
• adipose tissue of males has fewer macrophages than wild-type when fed a high fat diet, however weight of fat pads and numbers of adipose lymphocyte do not differ




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory