Analysis Tools
nervous system
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• mutants exposed to moderate intensity light show an accumulation of superoxide in rods at a level 3.5 times greater than in wild-type mice
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• mutants exhibit rod photoreceptor degeneration in response to moderate intensity light exposure that is not seen in wild-type mice
• mutants reared under a moderate light/dark cycle, but not dim/dark cycle conditions, develop severe retinal degeneration in less than 6 months
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vision/eye
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• mutants exposed to moderate intensity light show an accumulation of superoxide in rods at a level 3.5 times greater than in wild-type mice
|
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• mutants exhibit rod photoreceptor degeneration in response to moderate intensity light exposure that is not seen in wild-type mice
• mutants reared under a moderate light/dark cycle, but not dim/dark cycle conditions, develop severe retinal degeneration in less than 6 months
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Usher syndrome type 1 | DOID:0110826 |
OMIM:276900 |
J:181430 | |
