All Phenotypes Cks2<tm1Sir> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cks2^tm1Sir
targeted mutation 1, Steven I Reed
MGI:3586897

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cks2^tm1Sir/Cks2^tm1Sir	Not Specified	MGI:3607508

Allelic Composition	Cks2^tm1Sir/Cks2^tm1Sir
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cks2^tm1Sir mutation (0 available); any Cks2 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

azoospermia ( J:99997 )

• multinucleated spermatids are seen in some tubules

abnormal female meiosis ( J:99997 )

• meiosis arrests at metaphase I; however ovary morphology appears normal

arrest of male meiosis ( J:99997 )

• meiosis arrests at metaphase I during the first wave of spermatogenesis

reproductive system

azoospermia ( J:99997 )

• multinucleated spermatids are seen in some tubules

abnormal female meiosis ( J:99997 )

• meiosis arrests at metaphase I; however ovary morphology appears normal

arrest of male meiosis ( J:99997 )

• meiosis arrests at metaphase I during the first wave of spermatogenesis

testicular atrophy ( J:99997 )

female infertility ( J:99997 )

male infertility ( J:99997 )

endocrine/exocrine glands

testicular atrophy ( J:99997 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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